What to know about ZIP 40221
ZIP code 40221 covers Louisville, KY in Jefferson County.
It sits in telephone area code 502; U.S. House district KY-3; the LOUISVILLE media market.
Louisville city, KY
ZIP Code 40221 — Louisville city, KY Demographics & Data
Source: U.S. Census Bureau ACS 2019–2023 5-Year Estimates. Page data updated 2026-08-02.
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At a glance
Overview of ZIP Code 40221
Climate risk and migration signals
FEMA’s National Risk Index rates natural-hazard risk for Louisville city, KY as Relatively High (composite score 98.3), which is among the highest nationally. The strongest component scores on US5 are flood (99.1) and wildfire (56.1). These scores are county-linked NRI values published for planning context — all ZIP codes in the same county share the same composite score on US5. Useful when comparing insurance and disaster exposure across areas, not a substitute for a parcel-level flood or fire determination.
Climate normals for Louisville city, KY show limited published climate normals on US5.