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La Crosse city, WI

ZIP Code 54601 — La Crosse city, WI Demographics & Data

Source: U.S. Census Bureau ACS 2019–2023 5-Year Estimates. Page data updated 2026-08-02.

Middle ClassLarge CommunityLow Snow Area

Map, Quick Facts & Location

Quick Facts

Local time
Population
50,474
Median Income
$60,078
-20% vs US avg
Home Value
$220,200
-37% vs US avg
Median Rent
$856
-26% vs US avg
Median Age
32.2 yrs
-17% vs US avg
Area Code
Congress
Top Ancestry
GermanNorwegianIrish
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Location
Coordinates
43.8062, -91.1406
Elevation
1,307 ft
Land Area
73.5 sq mi
Water Area
1.3 sq mi (2% water)

At a glance

Population
50,474
Density
N/A
Median income
$60,078
-20% vs US avg
Home value
$220,200
-37% vs US avg
Median rent
$856
-26% vs US avg
Timezone

Overview of ZIP Code 54601

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What to know about ZIP 54601

ZIP code 54601 covers La Crosse, WI in La Crosse County with a population of about 50,474.

At a glance, the area shows median age of 32.2 versus a U.S. median of about 38.9.

It sits in telephone area code 608; U.S. House district WI-3; the LA CROSSE - EAU CLAIRE media market.

Income and economy in La Crosse, WI

Median household income in ZIP 54601 is about $60,078 — about 20% below the U.S. median ($75,149).

On socioeconomic markers, US5 shows a poverty rate of 19.2%; unemployment rate near 3.1%; 39.9% of adults with a bachelor’s degree or higher (about 6.2 points above the national share (33.7%)).

Labor and commute patterns include leading industry context around Healthcare, Retail trade, and Food services; about 10.3% of workers reporting work-from-home (about 4.9 points below the U.S. share (15.2%)); a mean commute of about 180.0 minutes (U.S. average near 26.8).

Housing and affordability in ZIP 54601

Median home value is about $220,200 — about 37% below the U.S. median home value ($348,079).

Housing tenure and rents show median gross rent around $856 (about 26% below the U.S. median rent ($1,163)), and owner-occupancy near 54.5% (about 10.9 points below the national owner-occupancy rate (65.4%)).

To comfortably buy a median-priced home in ZIP 54601 in La Crosse, WI, a household would need roughly $61,000 in annual income under a 20% down, 30-year loan at 6.8% (illustrative), keeping housing costs near 28% of income. Estimated monthly PITI is about $1,415. That is roughly in line with the local median household income ($60,078). Rates, taxes, insurance, and HOA fees vary — treat this as a planning estimate, not a lender quote.

Climate risk and migration signals

FEMA’s National Risk Index rates natural-hazard risk for La Crosse city, WI as Relatively Low (composite score 80.5), which is elevated versus much of the country. The strongest component scores on US5 are flood (74.0) and wildfire (11.8). These scores are county-linked NRI values published for planning context — all ZIP codes in the same county share the same composite score on US5. Useful when comparing insurance and disaster exposure across areas, not a substitute for a parcel-level flood or fire determination.

Climate normals for La Crosse city, WI show little to no average snow and around 37.5 inches of annual precipitation.

IRS migration statistics show a net inflow of about 2,944 for ZIP 54601 (La Crosse city, WI) on US5’s published series — a signal of people/tax filers moving in relative to those leaving. Inflows often track job growth, housing demand, or lifestyle migration; treat the figure as a directional indicator rather than a precise headcount.

Nearby (from this ZIP)

Airport LSE (7.7 miles (12.3 km)) · University of Wisconsin-La Crosse (4.6 miles (7.4 km)) · Effigy Mounds National Monument (50.2 miles (80.8 km)) · VA: River Valley Clinic (3.9 miles (6.3 km))

Full lists and map pins are in the Infrastructure section below.