ZIP Code 63341 — Defiance CDP, MO Demographics & Data

ZIP code 63341 covers Defiance, MO in St. Charles County with a population of about 3,554.

At a glance, the area shows median age of 47.7 versus a U.S. median of about 38.9.

It sits in telephone area code 636; U.S. House district MO-2; the ST. LOUIS media market.

Defiance, MO ranks among higher-income / higher-home-value communities on US5 (very high median household income (~$177,583)). Searchers often dig into housing affordability stretch, private schools, and neighborhood comparisons rather than entry-level rentals.

Median household income in ZIP 63341 is about $177,583 — about 136% above the U.S. median ($75,149).

On socioeconomic markers, US5 shows a poverty rate of 4.2%; unemployment rate near 2.5%; 53.9% of adults with a bachelor’s degree or higher (about 20.2 points above the national share (33.7%)).

Labor and commute patterns include leading industry context around Healthcare, Retail trade, and Manufacturing; about 21.1% of workers reporting work-from-home (about 5.9 points above the U.S. share (15.2%)); a mean commute of about 180.0 minutes (U.S. average near 26.8).

Median home value is about $552,600 — about 59% above the U.S. median home value ($348,079).

Housing tenure and rents show median gross rent around $1,055 (about 9% below the U.S. median rent ($1,163)), and owner-occupancy near 96.9% (about 31.5 points above the national owner-occupancy rate (65.4%)).

To comfortably buy a median-priced home in ZIP 63341 in Defiance, MO, a household would need roughly $152,000 in annual income under a 20% down, 30-year loan at 6.8% (illustrative), keeping housing costs near 28% of income. Estimated monthly PITI is about $3,550. That sits below the local median household income ($177,583), suggesting the typical household income is closer to a workable buy-in level under these assumptions. Rates, taxes, insurance, and HOA fees vary — treat this as a planning estimate, not a lender quote.

FEMA’s National Risk Index rates natural-hazard risk for Defiance CDP, MO as Relatively Moderate (composite score 92.6), which is among the highest nationally. The strongest component scores on US5 are flood (94.2) and wildfire (58.8). These scores are county-linked NRI values published for planning context — all ZIP codes in the same county share the same composite score on US5. Useful when comparing insurance and disaster exposure across areas, not a substitute for a parcel-level flood or fire determination.

Climate normals for Defiance CDP, MO show little to no average snow and around 44.4 inches of annual precipitation.

IRS migration statistics show a net inflow of about 161 for ZIP 63341 (Defiance CDP, MO) on US5’s published series — a signal of people/tax filers moving in relative to those leaving. Inflows often track job growth, housing demand, or lifestyle migration; treat the figure as a directional indicator rather than a precise headcount.