US5.com

Medical Assistants salary in South Carolina

Median: $41,160 / year · $19.79 / hr · 2025

10% below the U.S. average

Mean
$42,340
$20.36 / hr
Median hourly
$19.79 / hr
10th–90th percentile
$34,730 – $49,110
U.S. median
$45,690
Wage distribution (annual)
  • 10th percentile$34,730
  • Median$41,160
  • Mean$42,340
  • 90th percentile$49,110

U.S. median $45,690

Take-home estimate

$34,049

On a $41,160 OEWS median, single filer (2024). Not tax advice.

  • Federal income tax$2,955 (7.2%)
  • State income tax$1,007 (2.4%)
  • Social Security$2,552 (6.2%)
  • Medicare$597 (1.5%)
  • Net take-home$34,049 (82.7%)
  • Share of $41,160 gross (single filer). Not tax advice.

Open take-home calculator →

Related occupations in South Carolina

Dental Assistants $47,320 +$6,160 vs this job Dental Hygienists $84,340 +$43,180 vs this job Diagnostic Medical Sonographers $83,290 +$42,130 vs this job Emergency Medical Technicians and Paramedics $53,550 +$12,390 vs this job Licensed Practical and Licensed Vocational Nurses $61,820 +$20,660 vs this job Magnetic Resonance Imaging Technologists $83,550 +$42,390 vs this job Nurse Anesthetists $265,480 +$224,320 vs this job Nurse Practitioners $123,290 +$82,130 vs this job

ZIP codes in South Carolina

29072Lexington town29681Five Forks CDP29445Goose Creek city29485North Charleston city29732Rock Hill city29730Rock Hill city29483Summerville town29651Greer city29579Carolina Forest CDP29588Socastee CDP29223Dentsville CDP29464Mount Pleasant town

All South Carolina ZIP codes →

Highest-paying states for Medical Assistants

South Carolina ranks #37 of 51 states and DC with a published OEWS median ($41,160).

Medical Assistants median salary by state
RankStateMedian
#1 Highest Washington$59,290
#2Alaska$52,560
#3District of Columbia$51,050
#4Minnesota$50,480
#5Oregon$50,410
#6California$49,660
#7Massachusetts$49,460
#8Wisconsin$48,680
#9Hawaii$48,410
#10Colorado$48,400
#11New Hampshire$48,020
#12New York$48,000
#13Maine$47,580
#14Connecticut$47,430
#15Nebraska$47,370
#16Vermont$47,250
#17New Jersey$47,210
#18Rhode Island$47,190
#19Montana$46,820
#20Maryland$46,410
#21Illinois$46,090
#22North Dakota$45,980
#23Arizona$45,940
#24Iowa$45,480
#25Utah$45,360
#26Nevada$45,200
#27North Carolina$45,140
#28Indiana$45,110
#29Virginia$44,740
#30Idaho$44,700
#31Delaware$44,490
#32Pennsylvania$43,920
#33Florida$43,680
#34Ohio$42,810
#35South Dakota$41,870
#36Georgia$41,600
#37South Carolina$41,160
#38Wyoming$40,920
#39Missouri$40,440
#40Michigan$39,870
#41Tennessee$39,570
#42Texas$39,520
#43Kansas$39,510
#44Kentucky$39,270
#45New Mexico$39,230
#46Oklahoma$38,750
#47Arkansas$37,760
#48West Virginia$37,180
#49Louisiana$36,320
#50Alabama$36,100
#51 Lowest Mississippi$35,360

Frequently asked questions

What is the median medical assistants salary in South Carolina?
The OEWS median is $41,160 per year ($19.79 / hr) (2025), 10% below the U.S. average.
How much does a medical assistants make per hour in South Carolina?
The OEWS hourly median is $19.79 / hr.
Is this take-home pay?
No. OEWS is pre-tax. A single-filer estimate on this median is about $34,049 after federal, state, and FICA. Use the take-home calculator to change the gross.
How does medical assistants pay compare nationally?
The South Carolina median is 10% below the U.S. average versus the U.S. OEWS median of $45,690.
Which states pay medical assistantss the most?
Washington has the highest published OEWS median at $59,290. South Carolina ranks #37 of 51.
What is that salary worth after South Carolina living costs?
BEA all-items RPP is 93.8 (U.S. = 100), 6% below the U.S. average. $41,160 in South Carolina has about the same purchasing power as $43,904 at U.S. average prices.